Year of publication:
2008 2007 2006 2005 2004 2003 2002 2001 2000
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2008
Wheelock CE, Colvin ME, Sanborn JR, Hammock BD. 2008.
Substituted 3-phenylpropenoates and related analogs: electron ionization
mass spectral fragmentation and density functional theory calculations.
J Mass Spectrom. [PDF]
Harris TR, Aronov PA, Jones PD, Tanaka H, Arand M, Hammock BD.
2008. Identification of two epoxide hydrolases
in Caenorhabditis elegans that metabolize mammalian lipid signaling
molecules. Arch Biochem Biophys.[PDF]
Aronova S, Wedaman K, Aronov PA, Fontes K, Ramos K, Hammock BD,
Powers T. 2008. Regulation of Ceramide Biosynthesis
by TOR Complex 2. Cell Metab.;7(2):148-158. [PDF]. Preview [PDF]
Park EK, Watanabe T, Gee SJ, Schenker MB, Hammock BD. 2008.
Creatinine measurements in 24 h urine by liquid chromatography--tandem
Mass Spectrometry. J Agric Food Chem.;56(2):333-336.[PDF]
Corenblum MJ, Wise VE, Georgi K, Hammock BD, Doris PA, Fornage
M. 2008. Altered soluble epoxide hydrolase gene
expression and function and vascular disease risk in the stroke-prone
spontaneously hypertensive rat. Hypertension.;51(2):567-573.[PDF]
2007
Goodfriend TL, Pedersen TL, Grekin RJ, Hammock BD, Ball DL, Vollmer
A. 2007. Heparin, lipoproteins, and oxygenated
fatty acids in blood: a cautionary note. Prostaglandins Leukot Essent
Fatty Acids.;77(5-6):363-366 [PDF].
Anderson PJ, Lango J, Carkeet C, Britten A, Kräutler B, Hammock
BD, Roth JR. 2007. One pathway can incorporate
either adenine or dimethylbenzimidazole as an alpha-axial ligand
of B12 cofactors in Salmonella enterica. J Bacteriol.; 190(4):1160-1171.
[PDF] Editorial [PDF]
Kim I.H., Tsai H.J., Nishi K., Kasagami T., Morisseau C., Hammock
B.D. 2007. Abstract 1,3-Disubstituted Ureas Functionalized
with Ether Groups are Potent Inhibitors of the Soluble Epoxide Hydrolase
with Improved Pharmacokinetic Properties. J Med Chem.;50(21):5217-5226.
[PDF]
Chiamvimonvat N., Ho C.M., Tsai H.J., Hammock B.D. 2007.
The soluble epoxide hydrolase as a pharmaceutical target for hypertension.
J Cardiovasc Pharmacol. 50(3):225-37. [PDF]
Hwang S.H., Tsai H.J., Liu J.Y., Morisseau C., Hammock B.D.2007.
Orally Bioavailable Potent Soluble Epoxide Hydrolase Inhibitors.
J Med Chem. [PDF]
Zhang W., Koerner I.P., Noppens R., Grafe M., Tsai H.J., Morisseau
C., Luria A., Hammock B.D., Falck J.R., Alkayed N.J. 2007.
Soluble epoxide hydrolase: a novel therapeutic target in stroke.
J Cereb Blood Flow Metab. [PDF]
Dettmer K., Hanna D., Whetstone P., Hansen R., Hammock B.D. 2007.
Autism and urinary exogenous neuropeptides: development of an on-line
SPE-HPLC-tandem mass spectrometry method to test the opioid excess
theory. Anal Bioanal Chem. 388(8):1643-1651.[PDF]
Inceoglu B., Schmelzer K.R., Morisseau C., Jinks S.L., Hammock
B.D. 2007. Soluble epoxide hydrolase inhibition
reveals novel biological functions of epoxyeicosatrienoic acids
(EETs). Prostaglandins Other Lipid Mediat. 82(1-4):42-49.[PDF]
Luria A., Weldon S.M., Kabcenell A.K., Ingraham R.H., Matera D.,
Jiang H., Gill R., Morisseau C., Newman J.W., Hammock B.D. 2007.
Compensatory mechanism for homeostatic blood pressure regulation
in Ephx2 gene-disrupted mice. J Biol Chem., 282(5): 2891-2898.[PDF]
Andrew J. Phimister, Jozsef Lango, Eun Hui Lee, Michael Ernst-Russell,
Hiroshi Takeshima, Jianjie Ma, Paul D. Allen, and Isaac N. Pessah.
2007. Conformation-dependent stability of junctophilin
1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is
mediated by their hyper-reactive thiols. J. Biol. Chem., 282, 8667
– 8677.[PDF]
Dettmer K., Aronov P.A., Hammock B.D. 2007. Mass
spectrometry-based metabolomics. Mass Spectrom. Rev. 26: 51-78.
[PDF]
2006
Schmelzer K.R., Wheelock A.M., Dettmer K., Morin D., Hammock B.D.
2006. The role of inflammatory mediators in the
synergistic toxicity of ozone and 1-nitronaphthalene in rat airways.
Environ Health Perspect.114(9),1354-60. [PDF]
Inceoglu B., Jinks S.L., Schmelzer K.R., Waite T., Kim I.H., Hammock
B.D. 2006. Inhibition of soluble epoxide hydrolase
reduces LPS-induced thermal hyperalgesia and mechanical allodynia
in a rat model of inflammatory pain. Life Sci. [PDF]
Schmelzer K.R., Inceoglu B., Kubala L., Kim I.H., Jinks S.L.,
Eiserich J.P., Hammock B.D.2006. Enhancement of
antinociception by coadministration of nonsteroidal anti-inflammatory
drugs and soluble epoxide hydrolase inhibitors.Proc. Natl. Acad.
Sci. 103(37),13646-51. [PDF]
Koivunen, M.E., Dettmer K., Vermeulen R., Bakke B., Gee S.J.,
Hammock B.D. 2006. Improved methods for urinary
atrazine mercapturate analysis – Assessment of an enzyme-linked
immunosorbent assay (ELISA) and a novel liquid chromatography-mass
spectroscopy (LC-MS) method utilizing online solid phase extraction
(SPE). Anal. Chim. Acta 572:180-189. [PDF]
Watanabe T., Schulz D., Morisseau C., Hammock B.D. 2006.
High-throughput pharmacokinetic method: Cassette dosing in mice
associated with minuscule serial bleedings and LC/MS/MS analysis.
Anal. Chim. Acta. 559(1), 37-44. [PDF]
Davis B.B., Morisseau C., Newman J.W., Pedersen T.L., Hammock B.D.,
Weiss R.H. 2006. Attenuation of Vascular Smooth
Muscle Cell Proliferation by 1-Cyclohexyl-3-dodecyl Urea Is Independent
of Soluble Epoxide Hydrolase Inhibition. J. Pharmacol. Exp. Ther.
316(2), 815-821. [PDF]
Colleen, Carkeet, Stephen R. Dueker, Jozsef Lango, Bruce A. Buchholz,
Joshua W. Miller, Ralph Green, Bruce D. Hammock, John R. Roth, and
Peter J. Anderson. 2006. Human vitamin B12 absorption
measurement by accelerator mass spectrometry using specifically
labeled 14C-cobalamin. PNAS, 103(15), 5694-5699. [PDF]
Inceoglu, Bora. Jozsef Lango, Alina Rabinovich, Paul Whetstone,
Bruce D. Hammock. 2006. The neutralizing effect
of a polyclonal antibody raised against the N- terminal eighteen-aminoacid
residues of birtoxin towards the whole venom of Parabuthus transvaalicus.
Toxicon, 47, 144-149.
[PDF]
2005
Tran K.L., P. A. Aronov, H. Tanaka, J. W. Newman, B.D. Hammock,
C. Morisseau. 2005. Lipid sulfates and sulfonates
are allosteric competitive inhibitors of the N-terminal phosphatase
activity of the mammalian soluble epoxide hydrolase. Biochemistry.
44(36): 12179-12187. [PDF]
Schmelzer, K.R., L. Kubala, J.W. Newman,
I.H. Kim, J.P Eiserich, B.D. Hammock. 2005. Soluble
epoxide hydrolase is a therapeutic target for acute inflammation.
Proc. Natl. Acad. Sci. U S A. 102(28):9772-9777. [PDF]
Kim, I.H., F.R. Heirtzler, C. Morisseau, K. Nishi, H.
J. Tsai, B.D. Hammock. 2005. Optimization of
amide-based inhibitors of soluble epoxide hydrolase with improved
water solubility. J. Med. Chem. 48(10):3621-3629. [PDF]
Shearer, G.C., J.W. Newman, B.D.
Hammock, G.A. Kaysen. 2005. The graded effects
of proteinuria on HDL structure in nephrotic rats. J. Am. Soc. Nephrol.
16(5):1309-1319. [PDF]
Aronov, P.A., K.
Dettmer, J.A. Christiansen, A.J. Cornel, B.D. Hammock. 2005.
Development of HPLC/Tandem-MS method for the analysis of the larvicides
methoprene, hydroprene and kinoprene at trace levels using Diels-Alder
derivatization. J. Food Agric. Chem. 53(9):3306-3312. [PDF]
Smith, K.R., K.E. Pinkerton, T. Watanabe, T.L.
Pedersen , S.J. Ma, B.D. Hammock. 2005. Attenuation
of tobacco smoke-induced lung inflammation by treatment with a soluble
epoxide hydrolase inhibitor. Proc Natl Acad Sci U S A. 102(6):2186-2191.
[PDF]
Newman, J.W., C. Morisseau, B.D.
Hammock. 2005. Epoxide hydrolases: Their role and
interactions with lipid metabolism. Prog. Lipid Res. 44:1-51. [PDF]
Inceoglu B., J. Lango, I.N. Pessah
, B.D. Hammock. 2005. Three structurally related,
highly potent, peptides from the venom of Parabuthus transvaalicus
possess divergent biological activity.Toxicon. 45(6):727-733. [PDF]
2004
Dettmer, K. and B.D. Hammock. 2004.
Metabolomics—A new field within the “omics” sciences.
Environ. Health Perspect. 112:A396-A397. [PDF]
Newman, J.W., Stok J.E., Vidal J.D.,
Corbin C.J., Huang Q., Hammock B.D., Conley AJ. 2004. Cytochrome
p450-dependent lipid metabolism in preovulatory follicles. Endocrinology
145:5097-105. [PDF]
Seubert, J., B. Yang, A. Bradbury, J. Graves, L. Miller, S. Gabel,
R. Gooch, J. Foley, J. Newman, L.
Mao, H.A. Rockman, B.D. Hammock, E. Murphy, D.C. Zeldin. 2004. Enhanced
postischemic functional recovery in CYP2J2 transgenic hearts involves
mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway.
Circ Res 95:506-14. [PDF]
Dey A., Williams R.S., Pollock D.M., Stepp D.W., Newman
J.W., Hammock B.D., Imig J.D. 2004. Altered kidney CYP2C and
cyclooxygenase-2 levels are associated with obesity-related albuminuria.
Obes Res 12:1278-89. [PDF]
Zhao, X., T. Yammamoto, J.W. Newman,
I-H. Kim, T. Watanabe, B.D. Hammock, J. Stewart, J.S. Pollock, D.M.
Pollock, J.D. Imig. 2004. Soluble epoxide hydrolase inhibition protects
the kidney from hypertension-induced damage. J. Am. Soc. Nephrol.
15:1244-1253. [PDF]
Voss, A. A., Lango, J., Ernst-Russell,
M., Morin, D. and Pessah, I. N. 2004. Identification
of Hyperreactive Cysteines within Ryanodine Receptor Type 1 by Mass
Spectrometry. J. Biol. Chem., 279, 34514-34520. [PDF]
2003
Bora Inceoglu, Jozsef Lango, Jie
Jing, Lili Chen, Fuat Doymaz, Isaac N. Pessah, and Bruce D. Hammock.
2003. One scorpion, two venoms: Prevenom of Parabuthus
transvaalicus acts as an alternative type of venom with distinct
mechanism of action. Proc Nat Acad Sci USA. 100(3), 922-927. [PDF]
Sather, P.J., J.W. Newman, M.G.
Ikonomou. 2003. Congener based Aroclor quantification
and speciation techniques – A comparison of the strengths,
weaknesses, and proper use of two alternative approaches. Environ.
Toxicol. Chem. 37: 5678-5686. [PDF]
Viswanathan, S., B.D. Hammock, J.W. Newman,
P. Meerarani, M. Toborek, B.Hennig. 2003. Involvement
of CYP 2C9 in mediating the proinflammatory effects of linoleic
acid in vascular endothelial cells. J. Am. Coll. Nutr. 22(6):502-510.
[PDF]
Watanabe, T., C. Morisseau, J.W. Newman,
B.D. Hammock. 2003. In vitro metabolism of the
mammalian soluble epoxide hydrolase inhibitor 1-cyclohexyl-3-dodecyl-urea.
Drug Metab. Dispos. 31(7): 846-853. [PDF]
Newman, J.W., C. Morisseau, T.R.
Harris, B.D. Hammock. 2003. The soluble epoxide
hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid
phosphate phosphatase activity. Proc Nat Acad Sci USA. 100(4):1558-63.
[PDF]
2002
Newman, J.W., T.
Watanabe, B.D. Hammock. 2002. The simultaneous
quantification of cytochrome P450 dependent linoleate and arachidonate
metabolites in urine by high-performance liquid chromatography -
tandem mass spectroscopy. J Lipid Res. 43:1563-1578. [PDF]
Morisseau, C., M.H. Goodrow, J.W. Newman,
C.E. Wheelock, D.L. Dowdy, B.D. Hammock. 2002.
Structural refinement of urea based soluble epoxide hydrolase inhibitors.
Biochem. Pharmacol. 63(9):1599-1608. [PDF]
Pakenham, G., Lango, J., Bounarati,
M., Morin, D. and Buckpitt, A. 2002. Urinary Naphthalene
Mercapturates as Biomarkers of Exposure and Stereoselectivity of
Naphthalene Epoxidation, Drug Metabolism and Disposition, 30(3).
[PDF]
Inceoglu A.B., Hayashida,Y., Lango,
J., Ishida A.T., Hammock, B.D. 2002. A single
charged surface residue modifies the activity of ikitoxin, a beta-type
Na+ channel toxin from Parabuthus transvaalicus. European Journal
of Biochemistry (), 269(22), 5369-5376. [PDF]
Giri Shri N., Wang Qingjian, Xie Yan, Lango
Jozsef, Morin Dexter, Margolin Solomon B., Buckpitt Alan R. 2002.
Pharmacokinetics and metabolism of a novel antifibrotic drug pirfenidone,
in mice following intravenous administration. Biopharmaceutics &
Drug Disposition. 23(5), 203-211. [PDF]
2001
Watkins, S.M., B.D. Hammock, J.W. Newman,
J.B. German. 2001. Individual metabolism should
guide agriculture toward foods for improved health and nutrition.
Am J Clin Nutr. 74(3):283-6. [PDF]
Newman, J.W., and B.D. Hammock.
2001. Optimized thiol derivatizing reagent for
the mass spectral analysis of disubstituted epoxy fatty acids. J
Chromatogr A. 925(1-2):223-40. [PDF]
Morisseau, C., J.W. Newman, D.L.
Dowdy, M.H. Goodrow and B.D. Hammock. 2001. Inhibition
of microsomal epoxide hydrolases by ureas, amides and amines. Chem.
Res. Toxicol. 14:409-415. [PDF]
Slim, R., B.D. Hammock, M. Toborek, L.W. Robertson, J.W.
Newman, C.H.P. Morisseau, B.A. Watkins,V. Saraswathi, and B.
Hennig. 2001. The role of methyl-linoleic acid
epoxide and diol metabolites in the amplified toxicity of linoleic
acid and polychlorinated biphenyls to vascular endothelial cells.
Toxicol. Appl. Pharmacol. 171(3):184-193. [PDF]
Newman, J.W., D.L. Denton, C. Morisseau,
C.S. Koger, C.E. Wheelock, D.E. Hinton and B.D. Hammock. 2001.
Evaluation of fish models of soluble epoxide hydrolase inhibition.
Environ Health Persp. 109(1):61-66. [PDF]
Watanabe, T. and B.D. Hammock. 2001.
Rapid determination of soluble epoxide hydrolase inhibitors in rat
hepatic microsomes by high performance liquid chromatography with
electrospray tandem mass spectrometry. Anal. Biochem. 299:227-234.
[PDF]
Inceoglu, B., Lango, J., Wu, J.,
Hawkins, P., Southern, J. and Hammock, B. D. 2001.
Isolation and characterization of a novel type of neurotoxic peptide
from the venom of the South African scorpion Parabuthus transvaalicus
(Buthidae), European Journal of Biochemistry. 268 (20), 5407-5413.
[PDF]
2000
Yu, Z., F. Xu, L.M. Huse, C. Morisseau, A.J. Draper, J.W.
Newman, C. Parker, L. Graham, M.M. Engler, B.D. Hammock, D.C.
Zeldin and D.L. Kroetz. 2000. Soluble epoxide hydrolase
regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ.
Res. 87(11):992-998. [PDF]
Greene, J.F., J.W. Newman, K.C.
Williamson, and B.D. Hammock. 2000. Toxicity of
epoxy fatty acids and related compounds to cells expressing human
soluble epoxide hydrolase. Chem. Res. Toxicol. 13(4):217-226. [PDF]
Lohse, C., Jaeger, L.L., Staimer, N., Sanborn, J. R., Jones, A.
D., Lango, J., Gee, S. J. and Hammock,
B. D.2000. Development of a Class-Selective
Enzyme-Linked Immunosorbent Assay for Mercapturic Acids in Human
Urine, J. Agric. Food Chem, 48(12), 5913-5923. [PDF]
