Yanping Lin

 

Postdoctoral Researcher
Tel: +1-530-752-5109 (office) Fax: +1-530-752-1537
Email: elppalin@gmail.com

EDUCATION

• PhD in Pharmaceutical Engineering, 2009, Tianjin University, and Tianjin State Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin, China
• BS , in Pharmaceutical Engineering, 2004, Tianjin University, School of Chemical Engineering and Technology, Tianjin, China

 

RESEARCH EXPERIENCE

• Metabonomics for drug safety evaluation
  Establishing integrated metabonomic platform, profiling and identifying biomarkers in biofluids and elucidating toxic mechanisms in living organism.
  
• Pharmacokinetic and pharmacodynamic research of new drug entries
  Addressing PK and PD characteristics of potential compounds and performing pre-clinical and clinical evaluations of drugs.
  
• Identification of interesting metabolites
  Using pattern recognition methods to screen out metabolites and identify their structures.

SELECTED PUBLICATIONS

1. Lin Yan-Ping, Si Duan-Yun, Liu Chang-Xiao. Advances of liquid chromatography/mass spectrometry combined with chemometric approaches applied to metabonomics. Chinese Journal of Analytical Chemistry. 2007; 35: 1535-1539.

2. Yanping Lin, Duanyun Si, Changxiao Liu. An approach for detecting and identifying in vivo metabolites of brodimoprim via LC/ESI-MS with data-dependent scanning. Chemical Research in Chinese Universities. 2008; 24: 430-436

3. Yanping Lin, Duanyun Si, Changxiao Liu. Detection of synthetical compounds illegally mixed into Traditional Chinese Medicine antidiabetic preparations by liquid chromatography-mass spectrometry. Journal of Tianjin University. 2008; 41: 720-724

4. Yanping Lin, Duanyun Si, Zongpeng Zhang, Changxiao Liu. An integrated metabonomic method for profile of metabolic changes in carbon tetrachlorid induced rat urine.Toxicology. 2009; 256: 191-200.