Nils Helge Schebb

Tel: (530) 752-5109
Fax: (530) 752-8995

Email: nhschebb@ucdavis.edu

Education
1998 –2003
Undergraduate studies at the University of Münster in chemistry and food chemistry, biochemistry.
2004 – 2005
Graduate studies at the University of Karlsruhe in the group of Prof. Dr. Dr. M. Metzler. Diploma thesis entitled: “In vitro metabolism of the mycotoxins alternariol and alternariolmonomethylether”.
2006 –2009
PhD studies at the University of Münster in the group of Prof. Dr. U. Karst. PhD thesis entitled “LC-MS for biological activity detection in complex mixtures”
2006 - present
Post-graduate education program "Expert in Toxicology" (Fachtoxikologe) of the German Society of Pharmacology and Toxicology (DGPT).

Research Interest
Bioanalytical Chemistry, HPLC-Mass Spectrometry, Metabolism, Metablomics Toxicology and Food Chemistry

Ongoing Projects
Investigation of the metabolism, the pharmacokinetics and the biological effects of triclorcarban.

Scholarship and Funding
2001 - 2002: Scholarship from "German National Academic Foundation" (Studienstiftung des deutschen Volkes).
2006 - 2009: PhD Scholarship from "German National Academic Foundation"
2009 - present: Postdoc Scholarship from “German Academic Exchange Service”

Membership
German Chemical Society
- Society of Food Chemistry
- Division of Analytical Chemistry
German Society of Experimental and Clinical Pharmacology and Toxicology

Selected Publications

N.H. Schebb, D. Falck, E-M. Hein, U. Karst and H. Hayen (2009) A fast LC-ESI-MS Method for Monitoring Phospholipase A2 Activity. J. Chromatogr. A, 1216, 5249-5255.

N.H. Schebb, T. Vielhaber, A. Jousset and U. Karst (2009). Development of a Liquid Chromatography-Based Screening Methodology for Proteolytic Enzyme Activtiy. J. Chromatogr. A, 1216, 4407-4415.

N.H. Schebb, H. Faber, R. Maul, F. Heus, J. Kool, H. Irth and U. Karst (2008) Analysis of Glutathione Adducts of Patulin by Means of Liquid Chromatography (HPLC) with Biochemical Detection (BCD) and Electrospray Ionization Tandem Mass Spectrometry (ESI-MS/MS). Anal. Bioanal.Chem., 394, 1361-1373.

N.H. Schebb, F. Heus, T. Saenger, H. Irth, U. Karst and J. Kool (2008) Development of a Countergradient Parking System for Gradient Liquid Chromatography with Online Biochemical Detection of Serine Protease Inhibitors. Anal. Chem. 80, (17), 6764-72.

N. H. Schebb, D. Fischer, E-M. Hein, H. Hayen, J. Krieglstein, S. Klumpp and U. Karst (2008) Fast sample preparation and liquid chromatography–tandem mass spectrometry method for assaying cell lysate acetylcholine. J. Chromatogr. A, 1183, 100–107.

R. Maul, N. H. Schebb and S. E. Kulling (2008) Application of LC and GC hyphenated with mass spectrometry as tool for characterization of unknown derivatives of isoflavonoids. Anal. Bioanal.Chem 391, 239-250.

E. Pfeiffer, N. H. Schebb, J. Podlech and M. Metzler (2007) Novel oxidative in vitro metabolites of the mycotoxins alternariol and alternariol methyl ether. Mol Nutr Food Res 51, 307-316.

A. Liesener, A-M. Perchuc, R. Schöni, N. H. Schebb, M. Wilmer and U. Karst (2007) Screening of acetylcholinesterase inhibitors in snake venom by electrospray mass spectrometry. Pure Appl Chem 79,(12), 2339-2349.