Katja Dettmer

 

Post-Doctoral Researcher

Tel: (530) 752-5109

Fax: (530) 752-1537

email:

Education


Ph.D. at the University of Leipzig
Post-doctoral Research, University of California at Davis, funded by a scholarship of the German Research Foundation


Research


•Expertise in the environmental trace analysis of organic compounds using chromatographic and mass spectrometric techniques.
• Determine potential for the comprehensive characterization of metabolites -metabolomics- in bio-fluids as a tool for diagnosing disease including autism.
• Address fundamental questions regarding environmental factors in autism and the search for tools to assist in the diagnosis of autism.
• Development of analytical methods based on LC/MS and GC/MS as tools for metabolomics.
• Quantitative profiling of urinary tryptophan metabolites by on-line solid-phase extraction – liquid chromatography – tandem mass spectrometry for the assessment of metabolic dysfunctions associated with autism.
• Developing a sensitive technique for the analysis of vitamin D metabolites as a tool in obesity research
• General analytical laboratory support and student mentor.

Selected Publications


Dettmer, K.; Teichmann, A.; Engewald, W., Simultaneous analysis of volatile organic hydrocarbons and halocarbons in ambient air samples by use of adsorptive enrichment / thermal desorption and gas chromatographic dual column technique, submitted December 2003 to Journal Separation Science

Dettmer, K.; Engewald, W., Ambient air analysis of volatile organic compounds using adsorptive enrichment, Chromatographia (2003) in press

Drechsel, D.; Dettmer, K.; Engewald, W., Studies of Thermally assisted Hydrolysis and Methylation - GC-MS of fatty acids and triglycerides using different reagents and injection systems, Chromatographia (2003) in press

Bothe, F.; Dettmer, K.; Engewald, W., Determination of Perfume Oil in Household Products by Headspace Solid-Phase Microextraction and Fast Capillary Gas Chromatography, Chromatographia (2003) in press

Dettmer, K.; Engewald, W., Adsorbent materials commonly used in air analysis for adsorptive enrichment and thermal desorption of volatile organic compounds, Anal Bioanal Chem (2002) 373 :490–500

Drechsel, D.; Dettmer, K.; Engewald, W.; Bittner, Th.; Efer, J.: "GC Analysis of trichloroacetic acid in water samples by Large-Volume-Injection and thermal dexarboxylation in aprogrammed temperature vaporizer"; Chromatographia 54 (2001) 151-154

Dettmer, K.; Bittner, Th.; Engewald, W.: "Adsorptive enrichment and thermal desorption of low boiling oxygenated compounds, Possibilities and limitations"; Chromatographia 53 (2001) 322-325

K. Dettmer, Th. Knobloch, W. Engewald: "Stability of reactive low boiling hydrocarbons on carbon based adsorbents typically used for adsorptive enrichment and thermal desorption"; Fresenius J. Anal. Chem. 366 (2000) 70-78

K. Dettmer, U. Felix, W. Engewald, M. Mohnke: "Application of a Unique Selective PLOT Capillary Column for the Analysis of Oxygenated Compounds in Ambient Air"; Chromatographia Supplement 51 (2000) 221-227