Hsing-Ju
(Cindy) Tsai

(530)752-5109
(530)752-1537
EDUCATION/TRAINING:
2002 B.S. in
Department of Agricultural Chemistry, National Taiwan University,
Taiwan, ROC
2003 - present Ph.D. candidate, Pharmacology and Toxicology, University
of California, Davis
RESEARCH:
Pharmacokinetics
of soluble epoxide hydrolase inhibitors
Effects of soluble epoxide hydrolase inhibitors and epoxyeicosatrienoic
aicds on inflammatory disease
SELECTED PUBLICATIONS:
Kim IH, Nishi
K, Tsai HJ, Bradford T, Koda Y, Watanabe T, Morisseau C, Blanchfield
J, Toth I, Hammock BD. (2007). Design of bioavailable derivatives
of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor
of the soluble epoxide hydrolase. Bioorg Med Chem. 15(1):312-23.
Xu D, Li N,
He Y, Timofeyev V, Lu L, Tsai HJ, Kim IH, Tuteja D, Mateo RK, Singapuri
A, Davis BB, Low R, Hammock BD, Chiamvimonvat N. (2006). Prevention
and reversal of cardiac hypertrophy by soluble epoxide hydrolase
inhibitors. Proc Natl Acad Sci U S A.
Christophe Morisseau,
John W. Newman, Hsing-Ju Tsai, Preston A. Baecker and Bruce D. Hammock
. (2006).Peptidyl-urea based inhibitors of soluble epoxide hydrolases.
Bioorg Med Chem Lett. 16(20):5439-44.
Paul D. Jones,
Hsing-Ju Tsai, Zung N. Do, Christophe Morisseau, and Bruce D. Hammock.
(2006) Synthesis and SAR of conformationally restricted inhibitors
of soluble epoxide hydrolase. Bioorg Med Chem Lett. 16(19):5212-6.
Ki Chang Ahn,
Seung-Jin Ma, Hsing-Ju Tsai, Shirley J. Gee and Bruce D. Hammock
An immunoassay for a urinary metabolite as a biomarker of human
exposure to the pyrethroid insecticide permethrin. (2006). Anal
Bioanal Chem. 384(3):713-22.
In-Hae Kim, Fenton
R. Heirtzler, Christophe Morisseau, Kosuke Nishi, Hsing-Ju Tsai,
and Bruce D. Hammock (2005). Optimization of amide-based inhibitors
of soluble epoxide hydrolase with improved water solubility. J Med
Chem. 48(10):3621-9.